This DAG flat files is created for Lifestage system used in WormBase
This is an OWL translation of an ontology whose native representational form is .obo. The translation was performed using the oboInOwl xslt library. For details, see http://www.berkeleybop.org/obo-conv.cgi
adult
C. elegans Development DAG
all stages
All C. elegans development stages, including embryo, larva and adult stage.
embryo
The whole period of embryogenesis, from the formation of an egg till its hatch.
proliferating embryo
0-350min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 560 cells. From start of first cleavage till cleavage is over.
blastula embryo
0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage till the start of gastrulation.
1-cell embryo
Also called zygote. -50min till 0min of first cleavage at 20 Centigrade. Contains 1 cell.
2-cell embryo
0-20min after first cleavage at 20 Centigrade. Contains 2 cells.
4-cell embryo
20-40min after first cleavage at 20 Centigrade. Contains 4 cells.
8-cell embryo
~50 min after first cleavage at 20 Centigrade. Contains 8 cells.
12-cell embryo
~55 min after first cleavage at 20 Centigrade. Contains 12 cells.
28-cell embryo
100-105min after first cleaveage at 20 Centigrade. Contains 28 cells.
gastrulating embryo
100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation.
51-cell embryo
120-135min after first cleavage at 20 Centigrade. Contains 51 cells.
88-cell embryo
145-150min after first cleavage at 20 Centigrade. Contains 88 cells.
enclosing embryo
290-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage when embryo just finished gastulation and is enclosing.
late cleavage stage embryo
210-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage before the fast cleavage of cells finishes.
elongating embryo
350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation till elongation is over.
bean embryo
350-390min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. Emrbyo elongation started but have not formed comma shape yet. The shape of embryo looks like a lima bean. A stage right before comma embryo. Also called lima embryo or lima bean stage.
comma embryo
390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo.
1.5-fold embryo
420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.
2-fold embryo
460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.
3-fold embryo
520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.
fully-elongated embryo
620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.
postembryonic
The stage after hatch till death.
larva
From the time after hatch till becomes adult.
L1 larva
The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.
L1-L2 lethargus
The stage during L1-L2 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
L1-L2 molt
The stage when an animal shifts from L1 larva to L2 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
L2 larva
The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.
L2-L3 lethargus
The stage during L2-L3 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
L2-L3 molt
The stage when an animal shifts from L2 larva to L3 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
L2d-dauer lethargus
The stage during L2d-dauer molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
L2d-dauer molt
The stage when an animal shifts from L2d larva to dauer larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
dauer larva
A third stage larva specialized for dispersal and long term survival.
postdauer-L4 lethargus
The stage during postdauer-L4 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
postdauer-L4 molt
The stage when an animal shifts from post dauer stage to L4 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
L3 larva
The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.
L3-L4 lethargus
The stage during L3-L4 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
L3-L4 molt
The stage when an animal shifts from L3 larva to L4 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
L4 larva
The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.
L4 larva male
The fourth stage larva male. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.
L4-adult lethargus
The stage during L4-adult molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
L4-adult molt
The stage when an animal shifts from L4 larva to adult. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
L1-L2 ecdysis
The stage during L1-L2 molt, after the brief lethargus period, when an animal sheds off old cuticle.
L1-L2d molt
The stage when an animal shifts from L1 larva to L2d larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
L1-L2d lethargus
The stage during L1-L2d molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
L1-L2d ecdysis
The stage during L1-L2d molt, after the brief lethargus period, when an animal sheds off old cuticle.
L2d larva
A special second stage larva with altered physiology and developmental potential that leads to formation of dauer larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.
L2-L3 ecdysis
The stage during L2-L3 molt, after the brief lethargus period, when an animal sheds off old cuticle.
L2d-dauer ecdysis
The stage during L2d-dauer molt, after the brief lethargus period, when an animal sheds off old cuticle.
L3-L4 ecdysis
The stage during L3-L4 molt, after the brief lethargus period, when an animal sheds off old cuticle.
L4-adult ecdysis
The stage during L4-adult molt, after the brief lethargus period, when an animal shed off old cuticle.
postdauer-L4 ecdysis
The stage during postdauer-L4 molt, after the brief lethargus period, when an animal sheds off old cuticle.
post dauer stage
The stage right after an animal recovered from dauer but has not started transformation to L4 larva yet.
L2d-L3 molt
The stage when an animal shifts from L2d larva to L3 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
L2d-L3 lethargus
The stage during L2d-L3 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
L2d-L3 ecdysis
The stage during L2d-L3 molt, after the brief lethargus period, when an animal sheds off old cuticle.
adult male
The stage after an male animal is fully-developed and reaches maturity.
adult hermaphrodite
The stage after an hermaphrodite animal is fully-developed and reaches maturity.
pre-reproductive stage adult hermaphrodite
Very young adult hermaphrodites that do not have eggs in the uterus yet. At 20 Centigrade: 0 - 13 hours after L4-adult molt. 3 days after first cleaveage.
reproductive stage adult hermaphrodite
Adult hermaphrodites continuously laying fertilized eggs. hermaphrodite in egg laying stages--ususally up to 4/5 days after L4-adult molt at Centigrade. From the first fertilized egg is laid, til all sperms are used. At 20 Centigrade: 13 hours after L4-adult molt until about 5.4 days after the L4-adult molt. 3-8.4 days after first cleavage.
oocyte-laying stage adult hermaphrodite
When egg-laying is still going on but intermittent and during which a significant number of oocytes are laid. Included in reproductive stage adult hermaphrodite.
post-reproductive stage adult hermaphrodite
Adult hermaphrodites that contain no more sperm, thus stop egg-laying, but still alive. At 20 Centigrade: 5.4 days after L4-adult molt until the death. 8.4 - 13.2 (average wild type life span) days after first cleavage.
newly molted young adult hermaphrodite
At 20 Centigrade: 0-24 hours after L4-adult molt.
1-day post-L4 adult hermaphrodite
At 20 Centigrade: 24-48 hours after L4-adult molt. 4-5 days after first cleavage.
2-days post-L4 adult hermaphrodite
At 20 Centigrade: 48-72 hours after L4-adult molt. 5-6 days after first cleavage.
3-days post-L4 adult hermaphrodite
At 20 Centigrade: 72-96 hours after L4-adult molt. 6-7 days after first cleavage.
4-days post-L4 adult hermaphrodite
At 20 Centigrade: 96-120 hours after L4-adult molt. 7-8 days after first cleavage.
5-days post-L4 adult hermaphrodite
At 20 Centigrade: 5-6 days after L4-adult molt. 8-9 days after first cleavage.
4-7 days post-L4 adult hermaphrodite
At 20 Centigrade: 4-7 days after L4-adult molt. 7-10 days after first cleavage.
7-10 days post-L4 adult hermaphrodite
At 20 Centigrade: 7-10 days after L4-adult molt. 10-13 days after first cleavage. Usually this is the end of wild type C. elegans life span.
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